Table 1.

Associations between cartilage oligomeric matrix protein (COMP) and clinical variables at baseline in patients with early untreated rheumatoid arthritis. Spearman rank correlation rho values.

Characteristic	COMP at Baseline, n = 160	COMP at Baseline, Anti-CCP-positive, n = 93	COMP at Baseline, Anti-CCP-negative, n = 66
C-reactive protein	0.10	0.13	0.14
DAS28	0.28^**	0.28^**	0.27^*
No. swollen joints	0.39^**	0.32^**	0.47^**
No. tender joints	0.29^**	0.27^**	0.26^*
MRI synovitis score^†	0.25^**	0.22^*	0.32^*
MRI erosion score^†	0.25^**	0.37^**	0.13
MRI edema score^†	0.18^*	0.26^*	0.14
HAQ	0.11	0.20	0.04
VAS global	0.07	0.10	0.05
VAS pain	0.09	0.17	–0.02
VAS physician	0.34^**	0.25^*	0.44^**

↵* p ≤ 0.05;
↵** p ≤ 0.01.
↵† Contrast-enhanced MRI of nondominant wrist (n = 135). CCP: cyclic citrullinated peptides; DAS28: Disease Activity Score including 28 joints; VAS: visual analog scale score; HAQ: Health Assessment Questionnaire.