Descriptive data on the number of corner inflammatory lesions (CIL) recorded in the anterior cervical and lumbar spine at baseline and at followup MRI. Results are given for concordant and individual reads.
| CIL Data | Concordant Reads | First Reader | Second Reader | |||
|---|---|---|---|---|---|---|
| TNF-α Inhibitor Therapy n = 23 | Standard Therapy n = 27 | TNF-α Inhibitor Therapy n = 23 | Standard Therapy n = 27 | TNF-α Inhibitor Therapy n = 23 | Standard Therapy n = 27 | |
| Baseline MRI (total no. spinal sites) | 474 | 599 | 552 | 648 | 552 | 648 |
| Total number (%) of CIL | 32 (6.8) | 23 (3.8) | 86 (15.6) | 62 (9.6) | 56 (10.1) | 33 (5.1) |
| No. CIL per patient | ||||||
| Mean (SD) | 1.4 (1.53) | 0.85 (1.81) | 3.74 (2.63) | 2.30 (2.30) | 2.43 (1.97) | 1.22 (1.91) |
| Median (IQR) | 1 (0–2) | 0 (0–1) | 3 (2–5) | 2 (1–3) | 2 (1–3.5) | 1 (0–1.5) |
| Range | 0–6 | 0–9 | 0–10 | 0–10 | 0–7 | 0–9 |
| Followup MRI | ||||||
| Total number of CIL | 11 | 16 | 53 | 49 | 25 | 22 |
| CIL per patient | ||||||
| Mean (SD) | 0.48 (1.20) | 0.59 (1.45) | 2.30 (2.48) | 1.81 (2.06) | 1.09 (2.17) | 0.81 (1.66) |
| Median (IQR) | 0 (0–0) | 0 (0–1) | 1 (0–4) | 1 (0.5–2) | 0 (0–2) | 0 (0–1) |
| Range | 0–5 | 0–7 | 0–10 | 0–8 | 0–10 | 0–7 |
| No. completely resolved CIL | 14 | 7 | 42 | 22 | 44 | 20 |
| No. new CIL | 1 | 3 | 9 | 9 | 13 | 9 |
IQR: interquartile range; MRI: magnetic resonance imaging; TNF-α: tumor necrosis factor-α. First reader: PC; second reader: SJP.