Outcome measures used in clinical trials.
| Pain | Visual analog scale (VAS) pain, paper diary |
| VAS pain, electronic diary | |
| Numeric rating scale (NRS), daily diary | |
| Fibromyalgia Impact Questionnaire (FIQ) pain | |
| Brief Pain Inventory, pain severity scores | |
| Medical Outcomes Study Short-Form 36 (SF-36) bodily pain | |
| Tenderness | Dolorimetry — tender point threshold |
| Fatigue | VAS fatigue, daily diary |
| Fibromyalgia Impact Questionnaire fatigue | |
| SF-36 vitality | |
| Multidimensional Fatigue Inventory (MFI) | |
| Multidimensional Assessment of Fatigue | |
| Sleep | NRS of sleep quality, daily diary |
| FIQ morning rested feeling | |
| Medical Outcomes Study sleep scale | |
| Jenkins’ Sleep Problems Scale | |
| Depression | Beck Depression Inventory (BDI) |
| Hamilton Depression Rating Scale | |
| FIQ depression | |
| Hospital Anxiety and Depression Scale (HADS) depression | |
| MFI motivation | |
| Anxiety | FIQ anxiety |
| HADS anxiety | |
| Cognition | Multiple Abilities Self-Reported Questionnaire |
| MFI mental fatigue | |
| Stiffness | FIQ stiffness |
| Physical function | SF-36 physical function |
| FIQ physical function | |
| BDI pain interference with walking | |
| Social function | SF-36 social function |
| Sheehan Disability Scale (SDS) social and family life scales | |
| BDI pain interference with relations with other people | |
| Work function | SDS work/school scale |
| FIQ ability to do work | |
| BDI pain interference with work | |
| Activity | BDI pain interference with activity |
| MFI reduced activity | |
| SF-36 role emotional, role physical | |
| Quality of life | EuroQol Questionnaire 5 dimensions |