Expression Genotype Groups | SLE, n = 125 | Controls, n = 137 | p* |
---|---|---|---|
High | 82 (65.6) | 78 (56.9) | 0.236 |
YA/YA | 51 (40.8) | 48 (35.0) | |
YA/XA | 31 (24.8) | 30 (21.9) | |
Medium | 36 (28.8) | 45 (32.9) | |
XA/XA | 8 (6.4) | 7 (5.1) | |
YA/O | 28 (22.4) | 38 (27.8) | |
Low | 7 (5.6) | 14 (10.2) | |
XA/O | 6 (4.8) | 11 (8.0) | |
O/O | 1 (0.8) | 3 (2.2) |
A: wild-type; O: common designation for the variant alleles B (codon 54), C (codon 57), and D (codon 52); X and Y: designations for the variant alleles for promoter −221.
↵* p values derived by chi-squared test.