Table 2.

Changes in function and patient work productivity with etanercept treatment. Except for Fatigue Severity Scale, values apply to the 2-week period prior to the baseline or Month 24 visit.

Productivity Measuresn*Baseline MeanMonth 24 MeanMean Change (SD)p
Absence from work (working days)400.70.30.4 (2.6)0.3436
Unpaid work** by paid help (hours)273.21.21.9 (11.4)0.3830
Unpaid work** by unpaid help (hours)668.04.83.2 (12.1)0.0349
Impediments to paid and unpaid labour713.01.51.5 (1.7)< 0.001
Fatigue Severity Scale††1096.364.751.62 (2.33)< 0.001
  • * Subjects with available data at both baseline and Month 24.

  • ** Unpaid work defined as household work, shopping, childcare, and odd jobs around the house.

  • Score out of 8 (0 = no impediments; 8 = unable to do any of 4 surveyed activities).

  • †† Average of 9 questions relating to fatigue; score out of 10 (0 = not at all; 10 = yes, completely).