PT  - JOURNAL ARTICLE
AU  - Lisa K Stamp
AU  - John L O'Donnell
TI  - HLA-B27 associated spondyloarthropathy, vasculitis, and amyloid enteropathy: response to infliximab.
DP  - 2005 Feb 01
TA  - The Journal of Rheumatology
PG  - 382--385
VI  - 32
IP  - 2
4099  - http://www.jrheum.org/content/32/2/382.short
4100  - http://www.jrheum.org/content/32/2/382.full
SO  - J Rheumatol2005 Feb 01; 32
AB  - In 2000 we described a patient with HLA-B27 associated spondyloarthropathy (SpA) and severe ascending aortitis requiring surgical intervention. Despite continued immunosuppressive therapy she developed narrowing of the distal part of the right subclavian artery and proximal axillary artery secondary to active vasculitis. In addition, biopsy-proven amyloid gastroenteropathy developed causing persistent diarrhea and iron deficiency anemia. Treatment with infliximab resulted in resolution of joint symptoms and rapid improvement in laboratory markers of inflammation. Diarrhea settled more gradually, such that her bowel habit had normalized 16 months after therapy commenced.