%0 Journal Article %A Paul Rosen %A Robert J Hopkin %A David N Glass %A T Brent Graham %T Another patient with chromosome 18 deletion syndrome and juvenile rheumatoid arthritis. %D 2004 %J The Journal of Rheumatology %P 998-1000 %V 31 %N 5 %X Previously, 4 children with deletion of the long arm of chromosome 18 and chronic arthritis were reported. We present an 8-year-old girl with arthritis, atrial septal defect, external auditory canal atresia, and developmental delay. She is the fifth child reported with 18q- syndrome and juvenile rheumatoid arthritis. Evidence is mounting that genetic loci on chromosome 18 may play a role in the expression of complex autoimmune diseases. Idiopathic arthritis should be considered as a potential additional feature in 18q- syndrome. %U https://www.jrheum.org/content/jrheum/31/5/998.full.pdf