RT Journal Article
SR Electronic
T1 Destructive arthritis in a patient with Haim-munk syndrome.
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 814
OP 817
VO 31
IS 4
A1 Merav Lidar
A1 Abraham Zlotogorski
A1 Pnina Langevitz
A1 Nurit Tweezer-Zaks
A1 Gisele Zandman-Goddard
YR 2004
UL http://www.jrheum.org/content/31/4/814.abstract
AB Haim-Munk and Papillon-Lefèvre are 2 closely related syndromes, inherited in an autosomal recessive pattern, manifested by palmoplantar keratoderma and early, destructive periodontitis. Recently, mutations in the cathepsin C gene have been recognized in both syndromes. We describe a patient with Haim-Munk syndrome (palmar plantar keratosis and periodontitis) and destructive arthritis of the wrists and shoulder joints, an association that has not been previously described.