PT  - JOURNAL ARTICLE
AU  - Pham, Thao
AU  - Van Der Heijde, Désirée
AU  - Lassere, Marissa
AU  - Altman, Roy D
AU  - Anderson, Jennifer J
AU  - Bellamy, Nicholas
AU  - Hochberg, Marc
AU  - Simon, Lee
AU  - Strand, Vibeke
AU  - Woodworth, Thasia
AU  - Dougados, Maxime
AU - OMERACT-OARSI
TI  - Outcome variables for osteoarthritis clinical trials: The OMERACT-OARSI set of responder criteria.
DP  - 2003 Jul 01
TA  - The Journal of Rheumatology
PG  - 1648--1654
VI  - 30
IP  - 7
4099  - http://www.jrheum.org/content/30/7/1648.short
4100  - http://www.jrheum.org/content/30/7/1648.full
SO  - J Rheumatol2003 Jul 01; 30
AB  - Improvement in analysis and reporting results of osteoarthritis (OA) clinical trials has been recently obtained because of harmonization and standardization of the selection of outcome variables (OMERACT 3 and OARSI). Moreover, OARSI has recently proposed the OARSI responder criteria.This composite index permits presentation of results of symptom modifying clinical trials in OA based on individual patient responses (responder yes/no). The 2 organizations (OMERACT and OARSI) established a task force aimed at evaluating: (1) the variability of observed placebo and active treatment effects using the OARSI responder criteria; and (2) the possibility of proposing a simplified set of criteria. The conclusions of the task force were presented and discussed during the OMERACT 6 conference, where a simplified set of responder criteria (OMERACT-OARSI set of criteria) was proposed.