RT Journal Article SR Electronic T1 Economic evaluation of programs or interventions in the management of rheumatoid arthritis: defining a consensus-based reference case. JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 891 OP 896 VO 30 IS 4 A1 Andreas Maetzel A1 Peter Tugwell A1 Maarten Boers A1 Francis Guillemin A1 Doug Coyle A1 Mike Drummond A1 John B Wong A1 Sherine E Gabriel A1 OMERACT 6 Economics Research Group YR 2003 UL http://www.jrheum.org/content/30/4/891.abstract AB Improvement in the quality of economic evaluation could be documented as a consequence of international and national standardization efforts. One such effort is the recommendation that all economic evaluations in a given field produce findings in a standard format using a reference case. A reference case-based economic evaluation would adhere to specific settings with regard to outcomes, comparators, modeling techniques, and use of costs to facilitate comparisons among economic evaluations performed with the same objective. In the past, the Outcome Measures in Rheumatology Clinical Trials (OMERACT) consensus conference has successfully developed widely used, consensus-based outcome criteria for clinical improvement in rheumatoid arthritis (RA). Present efforts are being directed at the development of recommendations for the type and format of a reference case economic evaluation for newly developed disease modifying antirheumatic drugs (DMARD). This document discusses 13 important elements that experts considered to be relevant for the development of a reference case recommendation for economic evaluations in RA. We provide the rationale for each element and discuss how each element has been addressed in published economic evaluations of DMARD.