RT Journal Article
SR Electronic
T1 Health status of patients with juvenile rheumatoid arthritis at 1 and 5 years after diagnosis.
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 394
OP 400
VO 30
IS 2
A1 Bowyer, Suzanne L
A1 Roettcher, Philip A
A1 Higgins, Gloria C
A1 Adams, Barbara
A1 Myers, Linda K
A1 Wallace, Carol
A1 Rennebohm, Robert
A1 Moore, Terry L
A1 Pepmueller, Peri H
A1 Spencer, Charles
A1 Wagner-Weiner, Linda
A1 Rabinovich, Egla
A1 Passo, Murray
A1 Lovell, Daniel J
A1 McCurdy, Deborah
A1 Zemel, Lawrence
A1 Schikler, Kenneth N
A1 Szer, Ilona
A1 Kurtin, Paul
A1 Lindsley, Carol
YR 2003
UL http://www.jrheum.org/content/30/2/394.abstract
AB OBJECTIVE: To describe the health and functional status of children with juvenile rheumatoid arthritis (JRA) diagnosed in the early 1990s. METHODS: Patients were obtained from the Pediatric Rheumatology Disease Registry, a database of patients seen in pediatric rheumatology centers across the United States. Questionnaires designed to be filled out after retrospective chart review were sent to pediatric rheumatologists caring for children diagnosed with JRA between 1992 and 1997. RESULTS: We studied 703 patients -- 376 with pauciarticular onset (pauci), 232 with polyarticular onset (poly), and 95 with systemic onset JRA (systemic). At 1 year after diagnosis, half of the pauci and systemic patients no longer required medication, compared to 78% of the poly patients; 98% of the patients functioned in Steinbrocker classes I and II. Six percent of pauci, 27% of poly, and 11% of systemic patients had limitations in school function. Nearly 1/3 of poly patients already had joint space narrowing on radiograph. By 5 years after diagnosis, all pauci, 88% of poly, and 70% of systemic patients were in Steinbrocker classes I and II; but 6% of pauci, 28% of poly, and 44% of systemic patients had limitations in school function. Nearly 2/3 of poly and systemic patients had joint space narrowing. CONCLUSION: In these children treated prior to the era of biologic therapy, at 5 years after onset, > 25% of poly and nearly half of systemic patients had functional limitations that required modifications in their school schedule. Radiographically evident joint space damage was seen within a year of onset in poly patients, and by 5 years 2/3 of poly and systemic patients had damage.