RT Journal Article
SR Electronic
T1 Autoantibodies to NOR 90/hUBF: longterm clinical and serological followup in a patient with limited systemic sclerosis suggests an antigen driven immune response.
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1543
OP 1547
VO 29
IS 7
A1 Jehan H Dagher
A1 Ulrich Scheer
A1 Renate Voit
A1 Ingrid Grummt
A1 Lilian Lonzetti
A1 Yves Raymond
A1 Jean-Luc Senécal
YR 2002
UL http://www.jrheum.org/content/29/7/1543.abstract
AB We describe the clinical and serological followup of a 9-year-old girl with anti-nucleolar organizing region 90/human upstream-binding factor (anti-NOR 90/hUBF) who had features of systemic sclerosis over a period of 17 years, from childhood into adulthood. We review the associations of anti-UBF autoantibodies, and provide evidence that anti-NOR 90/UBF immune response is antigen driven.