RT Journal Article SR Electronic T1 Target organ associations in Turkish patients with Behçet's disease: a cross sectional study by exploratory factor analysis. JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 2393 OP 2396 VO 29 IS 11 A1 Recep Tunc A1 Erkani Keyman A1 Melike Melikoglu A1 Izzet Fresko A1 Hasan Yazici YR 2002 UL http://www.jrheum.org/content/29/11/2393.abstract AB OBJECTIVE: To look for target organ associations in Turkish patients with Behçet's disease (BD). METHODS: We studied target organ associations in 272 consecutive patients with BD. The occurrence of any of the clinical manifestations related to BD within the previous 3 months was sought by history questionnaire completed by a rheumatologist and by physical examination. Factor analysis was used to analyze the data. RESULTS: Four factors were identified by factor analysis of variables oral and genital ulcers, erythema nodosum, papulopustular skin lesions, uveitis, superficial and deep vein thrombosis, joint, arterial, neurological, and gastrointestinal involvement; the 4 identified factors explained 69% of the original information of the matrix. There was an association between oral ulcers, genital ulcers, and erythema nodosum (Factor 1); and between superficial and deep vein thrombosis (Factor 2). Uveitis was identified as a distinct feature, and was negatively associated with erythema nodosum (Factor 3) only among the females. There was also an association between papulopustular skin lesions and joint involvement (Factor 4). Factors 2 and 3 had higher scores in males (p = 0.001 and p = 0.009, respectively) versus females. CONCLUSION: We studied clinical features of BD in Turkish patients. The 4 factors we identified by factor analysis differ from a previous study from Israel, probably due to different methodologies used in the 2 studies. One factor described in our study, the association between papulopustular lesions and arthritis, supports findings of our recent study. A recognized association between superficial and deep vein thrombosis was also confirmed.