RT Journal Article
SR Electronic
T1 Acetabular osteitis in ankylosing spondylitis: does fibrillin figure in its pathogenesis?
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 2663
OP 2666
VO 28
IS 12
A1 P A Simkin
YR 2001
UL http://www.jrheum.org/content/28/12/2663.abstract
AB In the hip and sacroiliac joints, ankylosing spondylitis attacks the acetabulum over the femoral head and the ilium in preference to the sacrum. Both sites involve inflammation in bone subjacent to fibrocartilage with relative sparing of opposing, hyaline cartilage-surfaced mates. This disease appears to target connective tissues rich in fibrillin-1. A cell-mediated autoimmune response may be involved.