RT Journal Article
SR Electronic
T1 Dr. Eloseily et al reply
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP jrheum.2026-0555
DO 10.3899/jrheum.2026-0555
A1 Eloseily, Esraa
A1 Baker, Joy (Elizabeth)
A1 Schulert, Grant
A1 Grom, Alexei
YR 2026
UL http://www.jrheum.org/content/early/2026/07/09/jrheum.2026-0555.abstract
AB We thank Romano et al1 for their thoughtful comments and for sharing their relevant clinical experience with systemic juvenile idiopathic arthritis (sJIA) complicated by macrophage activation syndrome (MAS) with hepatic involvement. Their report of recurrent hepatic flares requiring combined therapeutic strategies extends our observations and further supports the emerging concept of interferon (IFN)-γ–driven liver pathology in sJIA-MAS.