<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Alhammadi, Nouf A.</style></author><author><style face="normal" font="default" size="100%">Gladman, Dafna D.</style></author><author><style face="normal" font="default" size="100%">Su, Jiandong</style></author><author><style face="normal" font="default" size="100%">Urowitz, Murray B.</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Isolated Neutropenia in Systemic Lupus Erythematosus</style></title><secondary-title><style face="normal" font="default" size="100%">The Journal of Rheumatology</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2023-03-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">459-460</style></pages><doi><style  face="normal" font="default" size="100%">10.3899/jrheum.220373</style></doi><volume><style face="normal" font="default" size="100%">50</style></volume><issue><style face="normal" font="default" size="100%">3</style></issue><abstract><style  face="normal" font="default" size="100%">To the Editor:Lymphopenia is the most commonly found leukocyte abnormality in patients with systemic lupus erythematosus (SLE). Neutropenia prevalence varied from 20% to 40% in a systematic literature review.1 Most of the neutropenia episodes occurring in patients with SLE are mild, but approximately 5% of patients may experience moderate (≥ 500/mm3 ≤ absolute neutrophil count [ANC] &lt; 1000/mm3) to severe neutropenia (ANC &lt; 500/mm3).2 The proposed pathogenesis of neutropenia in SLE includes increased peripheral destruction of granulocytes by circulating antineutrophil antibodies,3 increased margination or changes in marginal and splenic pool,4 and decreased granulocytopoiesis in the bone marrow.5,6Isolated neutropenia might be benign in certain ethnicities7; however, its role …</style></abstract></record></records></xml>