TY - JOUR T1 - Prologue: Evidence Informing the GRAPPA 2021 Treatment Recommendations, by Domain JF - The Journal of Rheumatology JO - J Rheumatol SP - 117 LP - 118 DO - 10.3899/jrheum.220486 VL - 50 IS - 1 AU - Enrique R. Soriano AU - Arthur Kavanaugh AU - Laura C. Coates Y1 - 2023/01/01 UR - http://www.jrheum.org/content/50/1/117.abstract N2 - Psoriatic arthritis (PsA) is a chronic inflammatory disease that is remarkably diverse in its presentation and course. Important domains of involvement include peripheral arthritis, skin and nail psoriasis, enthesitis, dactylitis, and axial arthritis, along with associated conditions such as inflammatory bowel disease (IBD) and anterior uveitis.1,2 Key comorbidities, such as metabolic syndrome, obesity, mental health issues, and others, affect disease outcomes and the approach to therapy.3,4 There has been tremendous progress in the understanding of PsA immunopathogenesis and the development of novel therapies and treatment strategies in recent years. In order to help clinicians keep abreast of key developments in PsA, a foundational mission of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) was the development of … ER -