RT Journal Article SR Electronic T1 Drs. Bessette and Kinch reply JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP jrheum.220909 DO 10.3899/jrheum.220909 A1 Louis Bessette A1 Cassandra D. Kinch YR 2022 UL http://www.jrheum.org/content/early/2022/10/10/jrheum.220909.abstract AB We thank Dr. Tchetina for their interest in our article,1 and we appreciate the opportunity to respond to their Letter to the Editor.2 In the letter and their recent publication, Tchetina et al describe the utility of gene expression analyses using peripheral blood mononuclear cells (PBMCs) from patients with rheumatoid arthritis (RA) to predict clinical response to tofacitinib (TOF).2,3