PT - JOURNAL ARTICLE AU - Louis Bessette AU - Cassandra D. Kinch TI - Drs. Bessette and Kinch reply AID - 10.3899/jrheum.220909 DP - 2022 Oct 15 TA - The Journal of Rheumatology PG - jrheum.220909 4099 - http://www.jrheum.org/content/early/2022/10/10/jrheum.220909.short 4100 - http://www.jrheum.org/content/early/2022/10/10/jrheum.220909.full AB - We thank Dr. Tchetina for their interest in our article,1 and we appreciate the opportunity to respond to their Letter to the Editor.2 In the letter and their recent publication, Tchetina et al describe the utility of gene expression analyses using peripheral blood mononuclear cells (PBMCs) from patients with rheumatoid arthritis (RA) to predict clinical response to tofacitinib (TOF).2,3