RT Journal Article
SR Electronic
T1 The burden of gout and its attributable risk factors in the Middle East and North Africa region, 1990-2019
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP jrheum.220425
DO 10.3899/jrheum.220425
A1 Fatemeh Amiri
A1 Ali-Asghar Kolahi
A1 Seyed Aria  Nejadghaderi
A1 Maryam Noori
A1 Alireza Khabbazi
A1 Mark J.M.  Sullman
A1 Jay S.  Kaufman
A1 Gary S.  Collins
A1 Saeid Safiri
YR 2022
UL http://www.jrheum.org/content/early/2022/08/28/jrheum.220425.abstract
AB Objective This study reported the burden of gout and its attributable risk factors, in the Middle East and North Africa (MENA) region between 1990 and 2019, by age, sex, and sociodemographic index (SDI). Methods Data on the prevalence, incidence, and years lived with disability (YLDs), due to gout, were obtained from the Global Burden of Disease study 2019 for the 21 countries in the MENA region, from 1990 to 2019. Results In 2019, the regional age-standardised point prevalence and annual incidence rates of gout were 509.1 and 97.7 per 100,000, which represent a 12.0% and an 11.1% increase since 1990, respectively. Moreover, in 2019 the regional age-standardised YLD rate was 15.8 per 100,000, an 11.7% increase since 1990. In 2019, Qatar and Afghanistan had the highest and lowest age-standardised YLD rates, respectively. Regionally, the age-standardised point prevalence of gout increased with age up to the oldest age group and it was more prevalent among males in all age groups. In addition, there was an overall positive association between SDI and the burden of gout between 1990 and 2019. In 2019, high body mass index (BMI) [46.1%] made the largest contributions to the burden of gout in the MENA region. Conclusion There were large inter-country variations in the burden of gout, but in general it has increased in MENA over the last three decades. This increase is in line with the global trends of gout. However, the age-standardised YLD rate change was higher in MENA than at the global level.