TY - JOUR T1 - Uveitis in Juvenile Psoriatic Arthritis: Still So Much To Learn JF - The Journal of Rheumatology JO - J Rheumatol SP - 661 LP - 662 DO - 10.3899/jrheum.220163 VL - 49 IS - 7 AU - Kamiar Mireskandari Y1 - 2022/07/01 UR - http://www.jrheum.org/content/49/7/661.abstract N2 - Psoriatic arthritis (PsA) is a systemic inflammatory disease that includes uveitis as one of its extraarticular associations. Studies involving predominantly adult patients report a significant association between the incidence of uveitis and psoriasis, the risk of which is greatest in patients with severe PsA.1,2 The literature on uveitis in children focuses mainly on risk factors for the more common forms of juvenile idiopathic arthritis (JIA) associated with uveitis and antinuclear antibody (ANA) positivity.3,4 Information on juvenile PsA–associated uveitis (JPsA-U) is scarce, with detailed ophthalmic findings restricted to small case series.5,6In this issue of The Journal of Rheumatology, Walscheid et al reported the results of a large population-based cohort study on 1862 patients with JPsA.7 Cross-sectional data from the German National Pediatric Rheumatological Database (NPRD) were used to describe prevalence and risk factors for JPsA-U. The authors report that their cohort from 2002 to 2014 had documented uveitis in 6.6% (122/1862). Patients with JPsA-U were more frequently ANA positive (60.3% vs 37.0%, P < 0.001) and younger at JPsA onset (5.3 vs 9.3 yrs, P < 0.001) compared to patients without uveitis. Indeed, uveitis developed more frequently in those aged < 5 years at JPsA onset (17.3% [73/423] vs 3.8% [49/1306], P < 0.001). … Address correspondence to Dr. K. Mireskandari, Department of Ophthalmology and Vision Sciences, Hospital for Sick Children and University of Toronto, 555 University Avenue, Toronto, ON M5G 1X8, Canada. Email: kamiar.mireskandari{at}sickkids.ca. ER -