TY - JOUR T1 - Which Attributes Are Most and Least Important to Patients When Considering Gout Flare Burden Over Time? A Best-worst Scaling Choice Study JF - The Journal of Rheumatology JO - J Rheumatol SP - 213 LP - 218 DO - 10.3899/jrheum.210605 VL - 49 IS - 2 AU - Jeremy Holyer AU - William J. Taylor AU - Angelo Gaffo AU - Graham Hosie AU - Anne Horne AU - Borislav Mihov AU - Isabel Su AU - Gregory D. Gamble AU - Nicola Dalbeth AU - Sarah Stewart Y1 - 2022/02/01 UR - http://www.jrheum.org/content/49/2/213.abstract N2 - Objective Several factors contribute to the patient experience of gout flares, including pain intensity, duration, frequency, and disability. It is unknown which of these factors are most important to patients when considering flare burden over time, including those related to the cumulative experience of all flares, or the experience of a single worst flare. This study aimed to determine which flare attributes are the most and least important to the patient experience of flare burden over time.Methods Participants with gout completed an anonymous online survey. Questions were aimed at identifying which attributes of gout flares, representing both individual and cumulative flare burden, were the most and least important over a hypothetical 6-month period. A best-worst scaling method was used to determine the importance hierarchy of the included attributes.Results Fifty participants were included. Difficulty doing usual activities during the worst flare and pain of the worst flare were ranked as the most important, whereas average pain of all flares was considered the least important. Overall, attributes related to the single worst gout flare were considered more important than attributes related to the cumulative impact of all flares.Conclusion When thinking about the burden of gout flares over time, patients rank activity limitation and pain experienced during their worst gout flare as the most important contributing factors, whereas factors related to the cumulative impact of all flares over time are relatively less important. ER -