TY - JOUR T1 - COVID-19 in women with rheumatic disease who are pregnant: Data from the COVID-19 Global Rheumatology Alliance JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.210480 SP - jrheum.210480 AU - Bonnie L. Bermas AU - Milena Gianfrancesco AU - Helen L. Tanner AU - Andrea M. Seet AU - Mathia C. Aguiar AU - Nasra K. Al Adhoubi AU - Samar Al Emadi AU - Bernardo M. Cunha AU - Rachael Flood AU - Daria A. Kusevich AU - Eoghan M. McCarthy AU - Naomi J. Patel AU - Eric Ruderman AU - Sebastian E. Sattui AU - Savino Sciascia AU - Faizah Siddique AU - Mario O. Valenzuela-Almada AU - Leanna M. Wise AU - Angus B. Worthing AU - JoAnn Zell AU - Suleman Bhana AU - Wendy Costello AU - Ali Duarte-Garcia AU - Rebecca Grainger AU - Laure Gossec AU - Jonathan S. Hausmann AU - Kimme Hyrich AU - Saskia Lawson-Tovey AU - Jean W. Liew AU - Emily Sirotich AU - Jeffrey Sparks AU - Paul Sufka AU - Zachary Wallace AU - Pedro M. Machado AU - Anja Strangfeld AU - Megan E.B. Clowse AU - Jinoos Yazdany AU - Philip C. Robinson Y1 - 2021/09/01 UR - http://www.jrheum.org/content/early/2021/08/26/jrheum.210480.abstract N2 - Objective To describe coronavirus disease-2019 (COVID-19) and pregnancy outcomes in patients with rheumatic disease who were pregnant at the time of infection. Methods Since March 2020 the COVID-19 Global Rheumatology Alliance (GRA) has collected cases of patients with rheumatic disease with COVID-19. We report details of pregnant women at the time of COVID-19 infection, including obstetric details separately ascertained from providers. Results We report on 39 patients, including 22 with obstetric detail available. The mean and median age was 33 years, range 24-45 years. Rheumatic disease diagnoses included: rheumatoid arthritis (n=9), systemic lupus erythematosus (n=9), psoriatic/other inflammatory arthritides (n=8) and anti-phospholipid antibody syndrome (n=6). Most had a term birth (16/22), with 3 pre-term births, one termination, one miscarriage and one woman yet to deliver at time of report. A quarter (n=10/39) of pregnant women were hospitalised following COVID-19 diagnosis. Two of 39 (5%) required supplemental oxygen (both hospitalised); no patient died. The majority did not receive specific medication treatment for their COVID-19 (n=32/39, 82%), seven patients received some combination of anti-malarials, colchicine, anti-IL-1beta, azithromycin, glucocorticoids, and lopinavir/ritonavir. Conclusion Women with rheumatic diseases who were pregnant at the time of COVID-19 had favourable outcomes. These data have limitations due to the small size and methodology, though they provide cautious optimism for pregnancy outcomes for women with rheumatic disease given the increased risk of poor outcomes that have been reported in other series of pregnant women with COVID-19. ER -