@article {Furer1014, author = {Victoria Furer and David Levartovsky and Jonathan Wollman and Irena Wigler and Daphna Paran and Ilana Kaufman and Ofir Elalouf and Sara Borok and Marina Anouk and Hagit Sarbagil-Maman and Mark Berman and Ari Polachek and Hagit Matz and Gideon Flusser and Ido Druckmann and Iris Eshed and Ori Elkayam}, title = {Prevalence of Nonradiographic Sacroiliitis in Patients With Psoriatic Arthritis: A Real-life Observational Study}, volume = {48}, number = {7}, pages = {1014--1021}, year = {2021}, doi = {10.3899/jrheum.200961}, publisher = {The Journal of Rheumatology}, abstract = {Objective. To establish the prevalence of nonradiographic sacroiliitis within a real-life sample of patients with psoriatic arthritis (PsA), using pelvic radiographs and magnetic resonance imaging (MRI) of sacroiliac joints (SIJs).Methods. This cross-sectional study included 107 consecutive adults with PsA (Classification Criteria for Psoriatic Arthritis criteria). Participants completed clinical and laboratory evaluation, pelvic radiographs scored for radiographic sacroiliitis according to the modified New York (mNY) criteria, and noncontrast MRI of SIJs, scored by the Berlin score and categorized into active sacroiliitis using the 2016 Assessment of Spondyloarthritis international Society (ASAS) criteria and the presence of structural sacroiliitis.Results. Radiographic sacroiliitis/mNY criteria were detected in 28.7\% (n = 29), confirmed by MRI-detected structural lesions in 72.4\% (n = 21). Active sacroiliitis was detected by MRI in 26\% (n = 28) of patients, with 11\% (n = 11) qualifying for nonradiographic sacroiliitis. Patients with radiographic and nonradiographic sacroiliitis had similar clinical characteristics, except for a longer duration of psoriasis (PsO) and PsA in the radiographic subgroup (PsO: 23.8 {\textpm} 12.5 vs 14.1 {\textpm} 11.7 yrs, P = 0.03; PsA: 12.3 {\textpm} 9.8 vs 4.7 {\textpm} 4.5 yrs, P = 0.02, respectively). Inflammatory back pain (IBP) was reported in 46.4\% (n = 13) with active sacroiliitis and 27\% (n = 3) with nonradiographic sacroiliitis. The sensitivity of IBP for detection of nonradiographic sacroiliitis was low (27\%) and moderate for radiographic sacroiliitis (52\%), whereas specificity ranged from 72\% to 79\% for radiographic and nonradiographic sacroiliitis, respectively.Conclusion. The prevalence of active sacroiliitis among a real-life population of patients with PsA was 26\%. However, the prevalence of nonradiographic sacroiliitis was low (11\%) compared to the radiographic sacroiliitis (28.7\%) seen in patients with longer disease duration. IBP was not a sensitive indicator for the presence of early-stage sacroiliitis that was commonly asymptomatic.}, issn = {0315-162X}, URL = {https://www.jrheum.org/content/48/7/1014}, eprint = {https://www.jrheum.org/content/48/7/1014.full.pdf}, journal = {The Journal of Rheumatology} }