RT Journal Article SR Electronic T1 Erectile Dysfunction in Men With Psoriatic Arthritis: A Population-based Cohort Study JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP jrheum.200903 DO 10.3899/jrheum.200903 A1 Katelynn M. Wilton A1 Sara J. Achenbach A1 Paras Karmacharya A1 Floranne C. Ernste A1 Eric L. Matteson A1 Cynthia S. Crowson YR 2020 UL http://www.jrheum.org/content/early/2020/12/10/jrheum.200903.abstract AB Objective To define the incidence of erectile dysfunction (ED) in a population-based cohort of men with psoriatic arthritis (PsA). Methods Data pertaining to demographics, ED, and potential confounding diagnosis were extracted from a comprehensive medical record system for a population-based cohort of men with PsA and an age-matched male comparator cohort. Cumulative incidence of ED adjusted for competing risk of death was compared between the 2 cohorts. Results There were 128 age-matched pairs of men with PsA and without PsA in the described cohorts. At baseline, there was a 7% prevalence of ED in men with PsA prior to diagnosis compared to a 3% prevalence of ED in the comparator cohort (P = 0.16). After PsA diagnosis/index date, diagnosis with PsA was associated with an increased risk of ED (age-adjusted HR 1.45, 95% CI 0.79–2.68), but this association did not reach statistical significance. This was based on 24 cases of ED in the men with PsA and 18 cases within the comparator cohort. No confounding factors or ED treatment strategies differed significantly between men with PsA and ED and comparators with ED. Conclusion Men with PsA may have an increased risk of ED, which was detected but likely underpowered in this study. Whether this difference is secondary to higher prevalence of traditional risk factors of ED in men with PsA compared to the general population will require further study.