PT  - JOURNAL ARTICLE
AU  - Perkins, Alexandra
AU  - Stevens, Anne
AU  - Ferguson, Polly M. 
AU  - Zhao, Yongdong
TI  - Urinary N-telopeptide as a Biomarker of Disease Activity in Patients with Chronic Nonbacterial Osteomyelitis Who Have Not Received Bisphosphonates
AID  - 10.3899/jrheum.191098
DP  - 2020 Oct 01
TA  - The Journal of Rheumatology
PG  - jrheum.191098
4099  - http://www.jrheum.org/content/early/2020/09/28/jrheum.191098.short
4100  - http://www.jrheum.org/content/early/2020/09/28/jrheum.191098.full
AB  - Chronic nonbacterial osteomyelitis (CNO) is a rare autoinflammatory disease that causes bone destruction, soft tissue swelling, and bone pain1. Diagnosis and treatment are hindered by a lack of a reliable laboratory test to assess disease activity. Bone inflammation in CNO is associated with increased osteoclastic activity and bone resorption, causing focal accelerated breakdown of bone collagen.