TY - JOUR T1 - Urinary N-telopeptide as a Biomarker of Disease Activity in Patients with Chronic Nonbacterial Osteomyelitis Who Have Not Received Bisphosphonates JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.191098 SP - jrheum.191098 AU - Alexandra Perkins AU - Anne Stevens AU - Polly M. Ferguson AU - Yongdong Zhao Y1 - 2020/10/01 UR - http://www.jrheum.org/content/early/2020/09/28/jrheum.191098.abstract N2 - Chronic nonbacterial osteomyelitis (CNO) is a rare autoinflammatory disease that causes bone destruction, soft tissue swelling, and bone pain1. Diagnosis and treatment are hindered by a lack of a reliable laboratory test to assess disease activity. Bone inflammation in CNO is associated with increased osteoclastic activity and bone resorption, causing focal accelerated breakdown of bone collagen. ER -