TY - JOUR T1 - CanVasc consensus recommendations for the management of antineutrophil cytoplasm antibody-associated vasculitis: 2020 update JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.200721 SP - jrheum.200721 AU - Arielle Mendel AU - Daniel Ennis AU - Ellen Go AU - Volodko Bakowsky AU - Corisande Baldwin AU - Susanne M. Benseler AU - David A. Cabral AU - Simon Carette AU - Marie Clements-Baker AU - Alison Clifford AU - Jan Willem Cohen Tervaert AU - Gerard Cox AU - Natasha Dehghan AU - Christine Dipchand AU - Navjot Dhindsa AU - Leilani Famorca AU - Aurore Fifi-Mah AU - Stephanie Garner AU - Louis-Philippe Girard AU - Clode Lessard AU - Patrick Liang AU - Damien Noone AU - Jean-Paul Makhzoum AU - Nataliya Milman AU - Christian A. Pineau AU - Heather N. Reich AU - Maxime Rhéaume AU - David B. Robinson AU - Dax G. Rumsey AU - Tanveer E. Towheed AU - Judith Trudeau AU - Marinka Twilt AU - Elaine Yacyshyn AU - Rae Yeung AU - Lillian Barra AU - Nader Khalidi AU - Christian Pagnoux Y1 - 2020/09/15 UR - http://www.jrheum.org/content/early/2020/09/10/jrheum.200721.abstract N2 - Objective In 2015, the Canadian Vasculitis Research Network (CanVasc) created recommendations for the management of antineutrophil cytoplasm antibody (ANCA)-associated vasculitides (AAV) in Canada. The current update aimed to revise existing recommendations and create additional recommendations, as needed, based on a review of new available evidence. Methods A needs assessment survey of CanVasc members informed questions for an updated systematic literature review (publications spanning May 2014-September 2019) using Medline, Embase, and Cochrane. New and revised recommendations were developed and categorized according to the level of evidence and strength of each recommendation. The CanVasc working group used a two-step modified Delphi procedure to reach >80% consensus on the inclusion, wording and grading of each new and revised recommendation. Results Eleven new and 16 revised recommendations were created, and 12 original (2015) recommendations were retained. New and revised recommendations are discussed in detail within this document. Five original recommendations were removed, of which 4 were incorporated into the explanatory text. The supplementary appendix for practical use was revised to reflect the updated recommendations. Conclusion The 2020 updated recommendations provide rheumatologists, nephrologists, and other specialists caring for patients with AAV in Canada with new management guidance, based on current evidence and consensus from Canadian experts. ER -