RT Journal Article
SR Electronic
T1 Risk of Diabetes Mellitus in Patients with Juvenile Idiopathic Arthritis
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1405
OP 1408
DO 10.3899/jrheum.190644
VO 47
IS 9
A1 Hemin Lee
A1 Yinzhu Jin
A1 Jun Liu
A1 Ezra M. Cohen
A1 Sarah K. Chen
A1 Seoyoung C. Kim
YR 2020
UL http://www.jrheum.org/content/47/9/1405.abstract
AB Objective. To examine the risk of type 1 diabetes (T1D) associated with juvenile idiopathic arthritis (JIA).Methods. Using the IBM MarketScan database, we compared JIA patients with asthma patients and healthy individuals for the risk of incident T1D.Results. We included patients with 15,210 JIA, 76,050 patients with asthma, and 76,050 healthy individuals matched 1:5 on age, sex, and index date. After adjustment for confounders, the multivariable HR of T1D associated with JIA was 1.48 (95% CI 0.86–2.56) versus asthma and 1.81 (95% CI 1.03–3.17) versus healthy individuals.Conclusion. JIA appears to be associated with an increased risk of T1D compared to patients with asthma and healthy children.