RT Journal Article
SR Electronic
T1 Longterm Outcomes of Temporomandibular Joints in Juvenile Idiopathic Arthritis: 17 Years of Followup of a Nordic Juvenile Idiopathic Arthritis Cohort
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP jrheum.190231
DO 10.3899/jrheum.190231
A1 Glerup, Mia
A1 Stoustrup, Peter
A1 Matzen, Louise H.
A1 Rypdal, Veronika
A1 Nordal, Ellen
A1 Frid, Paula
A1 Arnstad, Ellen Dalen
A1 Rygg, Marite
A1 Thorarensen, Olafur
A1 Ekelund, Maria
A1 Berntson, Lillemor
A1 Fasth, Anders
A1 Nilsson, Håkan
A1 Peltoniemi, Suvi
A1 Aalto, Kristiina
A1 Arte, Sirpa
A1 Toftedal, Peter
A1 Nielsen, Susan
A1 Kreiborg, Sven
A1 Herlin, Troels
A1 Pedersen, Thomas Klit
YR 2019
UL http://www.jrheum.org/content/early/2020/02/10/jrheum.190231.abstract
AB Objective To determine the prevalence of orofacial symptoms, dysfunctions, and deformities of the temporomandibular joint (TMJ) in juvenile idiopathic arthritis (JIA) 17 years after disease onset. Methods Drawn from a prospective, population-based Nordic JIA cohort with disease onset from 1997 to 2000, 420 consecutive cases were eligible for orofacial evaluation of TMJ involvement. The followup visit included demographic data, a standardized clinical orofacial examination, and full-face cone-beam computed tomography (CBCT). For comparison, 200 age-matched healthy controls were used. Results Of 420 eligible participants with JIA, 265 (63%) were included (mean age 23.5 ± 4.2 yrs) and completed a standardized clinical orofacial examination. Of these, 245 had a full-face CBCT performed. At least 1 orofacial symptom was reported by 33%. Compared to controls, the JIA group significantly more often reported TMJ pain, TMJ morning stiffness, and limitation on chewing. Further, among participants reporting complaints, the number of symptoms was also higher in JIA. The mean maximal incisal opening was lower in the JIA group (p < 0.001), and TMJ pain on palpation was more frequent. Condylar deformities and/or erosions were observed in 61% as assessed by CBCT, showing bilateral changes in about 70%. Risk factors of condylar deformities were orofacial dysfunction or biologic treatment; enthesitis-related arthritis was protective. Conclusion This study of the longterm consequences of TMJ involvement in a population-based JIA cohort reports persistence of comprehensive symptoms, dysfunctions, and damage of the TMJ into adulthood. We suggest interdisciplinary followup of JIA patients also in adulthood.