TY - JOUR T1 - Large Vessel Vasculitis Affecting the Aorta and Its Branches in Relapsing Polychondritis: Case Series and Systematic Review of the Literature JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.190862 SP - jrheum.190862 AU - Alessandro Tomelleri AU - Corrado Campochiaro AU - Silvia Sartorelli AU - Maurizio Papa AU - Giacomo De Luca AU - Giulio Cavalli AU - Elena Baldissera AU - Lorenzo Dagna Y1 - 2019/12/15 UR - http://www.jrheum.org/content/early/2019/12/09/jrheum.190862.abstract N2 - Objective To describe the features of large vessel vasculitis (LVV) affecting the aorta and its branches in relapsing polychondritis (RP) patients. Methods Retrospective data and systematic literature review. Results 21 patients were identified. LVV diagnosis was subsequent to RP and associated with extra-chondral involvement in the majority of patients. Supra-aortic vessels were more frequently involved (82%). 14 (67%) patients were treated with a csDMARD and 7 (33%) with a bDMARD. Vascular interventional procedures were performed in 10 (48%) patients. Prematurely death due to cardiovascular complications was reported in 3 (14%) cases. Conclusion Extra-aortic LVV is a serious and overlooked RP manifestation. All RP patients should be investigated for LVV. ER -