TY - JOUR T1 - Assessing Associations of Synovial Perfusion, Cartilage Quality, and Outcome in Rheumatoid Arthritis Using Dynamic Contrast-enhanced Magnetic Resonance Imaging JF - The Journal of Rheumatology JO - J Rheumatol SP - 15 LP - 19 DO - 10.3899/jrheum.180832 VL - 47 IS - 1 AU - Philipp Sewerin AU - Christoph Schleich AU - Ralph Brinks AU - Anja Müller-Lutz AU - Florian Fichter AU - Markus Eichner AU - Matthias Schneider AU - Benedikt Ostendorf AU - Stefan Vordenbäumen Y1 - 2020/01/01 UR - http://www.jrheum.org/content/47/1/15.abstract N2 - Objective. To assess associations of synovial perfusion, cartilage quality, and outcome in rheumatoid arthritis (RA).Methods. Synovial perfusion and cartilage quality were assessed by dynamic contrast-enhanced magnetic resonance imaging in metacarpophalangeal joints of 28 treatment-naive patients with RA at baseline and at 3 and 6 months after methotrexate. Analysis was by linear mixed modeling.Results. Synovial perfusion variables were associated with remission (p < 0.05) and cartilage quality (p < 0.004). Maximum synovial enhancement was associated to European League Against Rheumatism response (p < 0.05). Synovial perfusion improved in nonresponders over time (p < 0.05).Conclusion. Synovial perfusion relates to remission, response, and cartilage quality in a cohort of therapy-naive patients with early RA. ER -