RT Journal Article
SR Electronic
T1 The Risk of Diabetes Mellitus in Patients with Juvenile Idiopathic Arthritis
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP jrheum.190644
DO 10.3899/jrheum.190644
A1 Hemin Lee
A1 Yinzhu Jin
A1 Jun Liu
A1 Ezra M.  Cohen
A1 Sarah K.  Chen
A1 Seoyoung C.  Kim
YR 2019
UL http://www.jrheum.org/content/early/2019/11/25/jrheum.190644.abstract
AB Objective To examine the risk of type 1 diabetes (T1D) associated with juvenile idiopathic arthritis (JIA). Methods Using IBM MarketScan database, we compared JIA patients with asthma patients and healthy individuals for the risk of incident T1D. Results We included 15,210 JIA, 76,050 asthma and 76,050 healthy individuals 1:5 matched on age, sex, and index date. After adjusting for confounders, multivariable hazard ratio (95% confidence interval) of T1D associated with JIA was 1.48 (0.86-2.56) versus asthma and 1.81 (1.03-3.17) versus healthy individuals. Conclusion JIA appears to be associated with an increased risk of T1D compared to asthma and healthy children.