TY - JOUR T1 - Psoriatic Arthritis, Psoriatic Disease, or Psoriatic Syndrome? JF - The Journal of Rheumatology JO - J Rheumatol SP - 1428 LP - 1430 DO - 10.3899/jrheum.190054 VL - 46 IS - 11 AU - ENNIO LUBRANO AU - SILVIA SCRIFFIGNANO AU - FABIO MASSIMO PERROTTA Y1 - 2019/11/01 UR - http://www.jrheum.org/content/46/11/1428.abstract N2 - Psoriatic arthritis (PsA) is a multifaceted disease. Within this definition, PsA can be recognized by the identification of clinical hallmarks, and generally, rheumatologists diagnose it by the presence of typical skin lesions and articular inflammatory manifestations. This process could be a very easy task especially when some phenotypic manifestations and a detectable objective disease activity are present. Sometimes, the same disease can be very challenging when some manifestations such as pain, fatigue, or even enthesitis are predominant and associated with a less detectable disease activity.The British physician Verna Wright (1928–1998) is considered the father of the spondyloarthropathies. His interest started with PsA, and then with his junior colleagues, he made a fundamental contribution to this spectrum of diseases1.Over the past decade, an increased knowledge of PsA pathogenesis with the identification of various cytokines as targets to be treated has revolutionized the treatment strategy2. Therefore, the possibility of personalized medicine, with different phenotypes or biomarkers, has also been proposed3. Hence, there is a potential unmet need to redefine this condition4. In fact, we have moved from a simplistic concept of “arthritis” associated with psoriasis to a more comprehensive concept of “disease” because of the frequent association with extraarticular manifestations and comorbidities5. In … Address correspondence to Dr. E. Lubrano, Dipartimento di Medicina e Scienze della Salute “Vincenzo Tiberio,” Università degli Studi del Molise, Campobasso, Italy. E-mail: enniolubrano{at}hotmail.com ER -