RT Journal Article
SR Electronic
T1 Associations Between Cardiorespiratory Fitness and Arterial Stiffness in Ankylosing Spondylitis: A Cross-sectional Study
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1522
OP 1525
DO 10.3899/jrheum.170726
VO 45
IS 11
A1 Berg, Inger Jorid
A1 Semb, Anne Grete
A1 Sveaas, Silje H.
A1 Fongen, Camilla
A1 van der Heijde, Désirée
A1 Kvien, Tore K.
A1 Dagfinrud, Hanne
A1 Provan, Sella A.
YR 2018
UL http://www.jrheum.org/content/45/11/1522.abstract
AB Objective. To assess associations between cardiorespiratory fitness (CRF), measured as peak oxygen uptake (VO2peak), and cardiovascular disease (CVD) risk, measured by arterial stiffness, in patients with ankylosing spondylitis (AS).Methods. VO2peak was assessed by a maximal walking test on a treadmill. Arterial stiffness was measured noninvasively (Sphygmocor apparatus). Cross-sectional associations between VO2peak and arterial stiffness were analyzed using backward multivariable linear regression.Results. Among 118 participating patients, there were significant inverse associations between VO2peak and arterial stiffness, independent of traditional CVD risk factors and measures of disease activity.Conclusion. Reduced CRF may be related to increased risk of CVD in AS.