PT  - JOURNAL ARTICLE
AU  - Maria Prendecki
AU  - Leyre Martin
AU  - Anisha Tanna
AU  - Marilina Antonelou
AU  - Charles D.  Pusey
TI  - Increased Prevalence of Thyroid Disease in Patients with Antineutrophil Cytoplasmic Antibodies–associated Vasculitis
AID  - 10.3899/jrheum.170661
DP  - 2018 Mar 15
TA  - The Journal of Rheumatology
PG  - jrheum.170661
4099  - http://www.jrheum.org/content/early/2018/03/09/jrheum.170661.short
4100  - http://www.jrheum.org/content/early/2018/03/09/jrheum.170661.full
AB  - Objective Antineutrophil cytoplasmic antibodies (ANCA)–associated vasculitis (AAV) has been linked with thyroid disease as a result of antithyroid medications. We assessed the prevalence of thyroid disease in our patients with AAV. Methods Clinical records of 279 patients with AAV diagnosed between 1991 and 2014 were analyzed. Results Thyroid disease was identified in 21.5% of patients, but only 2 had previously received propylthiouracil. There was a greater proportion of female patients, patients with antimyeloperoxidase antibodies, and patients with renal disease in the group with thyroid disease. Conclusion Our data show a higher prevalence of thyroid disease in patients with AAV than the general population. This was not attributable to antithyroid drugs.