PT  - JOURNAL ARTICLE
AU  - Sibel Z. Aydin
AU  - Haner Direskeneli
AU  - Peter A. Merkel
AU  - on behalf of the International Delphi on Disease Activity Assessment in Large-vessel Vasculitis
TI  - Assessment of Disease Activity in Large-vessel Vasculitis: Results of an International Delphi Exercise
AID  - 10.3899/jrheum.161269
DP  - 2017 Dec 01
TA  - The Journal of Rheumatology
PG  - 1928--1932
VI  - 44
IP  - 12
4099  - http://www.jrheum.org/content/44/12/1928.short
4100  - http://www.jrheum.org/content/44/12/1928.full
SO  - J Rheumatol2017 Dec 01; 44
AB  - Objective. To arrive at consensus for candidate outcomes for disease activity assessment in large-vessel vasculitis (LVV) in clinical trials.Methods. A Delphi survey including 99 items was circulated among international experts for 3 rounds.Results. Fifty-seven items were accepted for both giant cell arteritis and Takayasu arteritis. Sixty-seven percent of experts voted to have a common approach for both diseases with additional disease-specific items such as weight loss, scalp tenderness/necrosis, morning stiffness, dizziness, visual symptoms, and imaging.Conclusion. This study highlights similarities and differences in experts’ perspectives for assessing clinical activity in LVV and may guide a consensus-driven core set of validated outcomes.