RT Journal Article
SR Electronic
T1 Updating the Psoriatic Arthritis (PsA) Core Domain Set: A Report from the PsA Workshop at OMERACT 2016
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1522
OP 1528
DO 10.3899/jrheum.160904
VO 44
IS 10
A1 Orbai, Ana-Maria
A1 de Wit, Maarten
A1 Mease, Philip J.
A1 Callis Duffin, Kristina
A1 Elmamoun, Musaab
A1 Tillett, William
A1 Campbell, Willemina
A1 FitzGerald, Oliver
A1 Gladman, Dafna D.
A1 Goel, Niti
A1 Gossec, Laure
A1 Hoejgaard, Pil
A1 Leung, Ying Ying
A1 Lindsay, Chris
A1 Strand, Vibeke
A1 van der Heijde, Désirée M.
A1 Shea, Bev
A1 Christensen, Robin
A1 Coates, Laura
A1 Eder, Lihi
A1 McHugh, Neil
A1 Kalyoncu, Umut
A1 Steinkoenig, Ingrid
A1 Ogdie, Alexis
YR 2017
UL http://www.jrheum.org/content/44/10/1522.abstract
AB Objective. To include the patient perspective in accordance with the Outcome Measures in Rheumatology (OMERACT) Filter 2.0 in the updated Psoriatic Arthritis (PsA) Core Domain Set for randomized controlled trials (RCT) and longitudinal observational studies (LOS).Methods. At OMERACT 2016, research conducted to update the PsA Core Domain Set was presented and discussed in breakout groups. The updated PsA Core Domain Set was voted on and endorsed by OMERACT participants.Results. We conducted a systematic literature review of domains measured in PsA RCT and LOS, and identified 24 domains. We conducted 24 focus groups with 130 patients from 7 countries representing 5 continents to identify patient domains. We achieved consensus through 2 rounds of separate surveys with 50 patients and 75 physicians, and a nominal group technique meeting with 12 patients and 12 physicians. We conducted a workshop and breakout groups at OMERACT 2016 in which findings were presented and discussed. The updated PsA Core Domain Set endorsed with 90% agreement by OMERACT 2016 participants included musculoskeletal disease activity, skin disease activity, fatigue, pain, patient’s global assessment, physical function, health-related quality of life, and systemic inflammation, which were recommended for all RCT and LOS. These were important, but not required in all RCT and LOS: economic cost, emotional well-being, participation, and structural damage. Independence, sleep, stiffness, and treatment burden were on the research agenda.Conclusion. The updated PsA Core Domain Set was endorsed at OMERACT 2016. Next steps for the PsA working group include evaluation of PsA outcome measures and development of a PsA Core Outcome Measurement Set.