RT Journal Article
SR Electronic
T1 Longterm Effectiveness of Herpes Zoster Vaccine among Patients with Autoimmune and Inflammatory Diseases
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 1083
OP 1087
DO 10.3899/jrheum.160685
VO 44
IS 7
A1 Huifeng Yun
A1 Fenglong Xie
A1 John W. Baddley
A1 Kevin Winthrop
A1 Kenneth G. Saag
A1 Jeffrey R. Curtis
YR 2017
UL http://www.jrheum.org/content/44/7/1083.abstract
AB Objective. The protection duration of herpes zoster (HZ) vaccination is unclear among patients with autoimmune (AI) diseases.Methods. Using 2006–2013 Medicare data, HZ vaccinated patients with AI were matched 1:2 to unvaccinated HZ. Incidence rates (IR) and adjusted risk ratios over time were calculated using Poisson regression.Results. Of 59,627 vaccinated patients, crude IR increased from 0.75/100 person-years during the first year post-vaccination to 1.25 during the seventh year. Vaccinated patients had a significantly lower risk of HZ compared with the unvaccinated through 5 years.Conclusion. HZ vaccination was significantly protective only for about 5 years among patients with AI.