TY - JOUR T1 - Poor Predictive Value of Isolated Adventitial and Periadventitial Infiltrates in Temporal Artery Biopsies for Diagnosis of Giant Cell Arteritis JF - The Journal of Rheumatology JO - J Rheumatol SP - 1039 LP - 1043 DO - 10.3899/jrheum.170061 VL - 44 IS - 7 AU - Claire Le Pendu AU - Véronique Meignin AU - Solange Gonzalez-Chiappe AU - Adrian Hij AU - Françoise Galateau-Sallé AU - Alfred Mahr Y1 - 2017/07/01 UR - http://www.jrheum.org/content/44/7/1039.abstract N2 - Objective. We investigated the diagnostic value of inflammation limited to the adventitia (ILA), and isolated vasa vasorum or small-vessel vasculitis (VVV, SVV) in temporal artery biopsies (TAB) for giant cell arteritis (GCA).Methods. Two pathologists reviewed consecutive first TAB. Using the clinical diagnoses as the gold standard, positive predictive values (PPV) were calculated.Results. Among the 75 patients without classic TAB features of GCA, 8 had GCA diagnoses. The PPV of ILA, VVV, and SVV seen by either or both pathologists were 17%, 0%, and 7%, and 17%, 0%, and 10%, respectively.Conclusion. (Peri)adventitial infiltrates in TAB poorly predict GCA. ER -