TY - JOUR T1 - Basic and Translational Science: A Report from the GRAPPA 2016 Annual Meeting JF - The Journal of Rheumatology JO - J Rheumatol SP - 679 LP - 683 DO - 10.3899/jrheum.170143 VL - 44 IS - 5 AU - James G. Krueger AU - Bruce Kirkham AU - Christopher T. Ritchlin Y1 - 2017/05/01 UR - http://www.jrheum.org/content/44/5/679.abstract N2 - Rapid advances in effective treatments for psoriasis and psoriatic arthritis (PsA) have emerged from improved understanding of cell subsets and critical mediators that promote tissue inflammation and destruction. More specifically, increased knowledge of innate immunity and the important involvement of cytokines in the interleukin (IL)-23–IL-17 axis as key mediators of psoriatic plaque and joint inflammation in both psoriasis and PsA have led to new theories of immunopathogenesis. Herein we summarize recent discussions on IL-17–related pathways and their relationship to psoriasis and PsA. ER -