PT - JOURNAL ARTICLE AU - HANI EL-GABALAWY AU - LYN C. GUENTHER AU - CHARLES N. BERNSTEIN TI - Epidemiology of Immune-Mediated Inflammatory Diseases: Incidence, Prevalence, Natural History, and Comorbidities AID - 10.3899/jrheum.091461 DP - 2010 May 01 TA - The Journal of Rheumatology PG - 2--10 VI - 85 4099 - http://www.jrheum.org/content/85/2.short 4100 - http://www.jrheum.org/content/85/2.full SO - J Rheumatol2010 May 01; 85 AB - Immune-mediated inflammatory diseases (IMID) present a group of common and highly disabling chronic conditions that share inflammatory pathways. Several incidence and prevalence studies of IMID during the past decades have reported a considerable variation of the disease occurrence among different populations. Overall, the estimated prevalence of IMID in Western society is 5%–7%. This article provides an overview of studies of the incidence, prevalence, natural history, and comorbidities of IMID.