PT  - JOURNAL ARTICLE
AU  - Michael J Pinkoski
AU  - Douglas R Green
TI  - Apoptosis in the regulation of immune responses.
DP  - 2005 Mar 01
TA  - The Journal of Rheumatology
PG  - 19--25
VI  - 74
4099  - http://www.jrheum.org/content/74/19.short
4100  - http://www.jrheum.org/content/74/19.full
SO  - J Rheumatol2005 Mar 01; 74
AB  - Apoptosis, or programmed cell death, is an active process required for the regulation of immune responses. T cell apoptosis may represent a protective mechanism that limits peripheral damage by T cells during immune response. The underlying biological processes responsible for morphological aspects of apoptosis are becoming better defined. Concepts reviewed here include caspase activation, death pathways, and crosstalk between death ligands and their receptors.