PT  - JOURNAL ARTICLE
AU  - Dafna D. Gladman
TI  - Toward Treating to Target in Psoriatic Arthritis
AID  - 10.3899/jrheum.150626
DP  - 2015 Nov 01
TA  - The Journal of Rheumatology
PG  - 14--16
VI  - 93
4099  - http://www.jrheum.org/content/93/14.short
4100  - http://www.jrheum.org/content/93/14.full
SO  - J Rheumatol2015 Nov 01; 93
AB  - The concept “treat to target” in rheumatology was first developed for rheumatoid arthritis. A similar attempt to develop such an approach for spondyloarthritis was unsuccessful because the assessment tools and target of therapy had not been developed. In psoriatic arthritis (PsA), composite indices to assess disease activity, disease state, and responsiveness have been developed and can be used as targets. There are a number of definitions for remission, but none are widely accepted. However, a state of minimal disease activity has been defined. There is evidence now that the treat-to-target approach is feasible, using the minimal disease activity state as a target and devising a tight control approach, which is superior to standard of care. Further work will determine the best target and the best approach to reach it.