TY - JOUR T1 - Reconciling Healthcare Professional and Patient Perspectives in the Development of Disease Activity and Response Criteria in Connective Tissue Disease–related Interstitial Lung Diseases JF - The Journal of Rheumatology JO - J Rheumatol DO - 10.3899/jrheum.131251 SP - jrheum.131251 AU - Lesley Ann Saketkoo AU - Shikha Mittoo AU - Sid Frankel AU - Daphne LeSage AU - Catherine Sarver AU - Kristine Phillips AU - Vibeke Strand AU - Eric L. Matteson AU - the OMERACT Connective Tissue Disease–Interstitial Lung Diseases Working Group Y1 - 2014/02/01 UR - http://www.jrheum.org/content/early/2014/01/29/jrheum.131251.abstract N2 - Interstitial lung diseases (ILD), including those related to connective tissue disease (CTD), and idiopathic pulmonary fibrosis (IPF) carry high morbidity and mortality. Great efforts are under way to develop and investigate meaningful treatments in the context of clinical trials. However, efforts have been challenged by a lack of validated outcome measures and by inconsistent use of measures in clinical trials. Lack of consensus has fragmented effective use of strategies in CTD-ILD and IPF, with a history of resultant difficulties in obtaining agency approval of treatment interventions. Until recently, the patient perspective to determine domains and outcome measures in CTD-ILD and IPF had never been applied. Efforts described here demonstrate unequivocally the value and influence of patient involvement on core set development. Regarding CTD-ILD, this is the first OMERACT working group to directly address a manifestation/comorbidity of a rheumatic disease (ILD) as well as a disease not considered rheumatic (IPF). The OMERACT 11 proceedings of the CTD-ILD Working Group describe the forward and lateral process to include both the medical and patient perspectives in the urgently needed identification of a core set of preliminary domains and outcome measures in CTD-ILD and IPF. ER -