RT Journal Article
SR Electronic
T1 Etanercept Compared to Intraarticular Corticosteroid Injection in Rheumatoid Arthritis: Double-blind, Randomized Pilot Study
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP jrheum.100828
DO 10.3899/jrheum.100828
A1 Christian H. Roux
A1 Veronique Breuil
A1 Laure Valerio
A1 Nicolas Amoretti
A1 Olivier Brocq
A1 Christine Albert
A1 Christian Grisot
A1 Yacine Allam
A1 Patrick Chevalier
A1 Christian Pradier
A1 Lianna Euller-Ziegler
YR 2011
UL http://www.jrheum.org/content/early/2011/03/08/jrheum.100828.abstract
AB Objective To compare etanercept (anti-tumor necrosis factor-α) with intraarticular (IA) corticosteroid injections to treat rheumatoid arthritis (RA). Methods Patients with RA who had persistent monoarthritis received etanercept or IA corticosteroid injections. Efficacy was compared at Weeks 4 and 24. Results Thirty-four patients were included (8 dropped out). Mean age was 58.8 years. No difference between groups was found at Weeks 4 or 24, but both groups showed significant improvement at Weeks 4 and 24 compared to baseline. Conclusion Etanercept and IA steroid injections resulted in significant improvement at Week 4 that persisted to Week 24. There was no significant difference in outcome between the groups.