TY - JOUR T1 - Single-joint Assessment for the Evaluation of Intraarticular Treatment: Responsiveness and Discrimination of the Composite Change Index JF - The Journal of Rheumatology JO - J Rheumatol SP - 1672 LP - 1676 DO - 10.3899/jrheum.140956 VL - 42 IS - 9 AU - Caroline J. Aalbers AU - Danielle M. Gerlag AU - Margriet J. Vervoordeldonk AU - Paul P. Tak AU - Robert B. Landewé Y1 - 2015/09/01 UR - http://www.jrheum.org/content/42/9/1672.abstract N2 - Objective. To investigate responsiveness, discrimination, and construct validity of a composite change index (CCI) for the assessment of single-joint involvement in inflammatory arthritis.Methods. Evaluation of standardized response means (SRM), Guyatt effect size, and Spearman rank correlation coefficient in a randomized controlled trial investigating the effect of an intraarticular etanercept injection.Results. The CCI showed a high SRM (1.68) and high Guyatt effect size (2.72). Both visual analog scale of pain and functionality had a moderate Guyatt effect size (2.06, 2.44) and high SRM (0.81, 0.97).Conclusion. This study supports the use of the CCI as a single-joint assessment after single-joint intervention. Clinical trial registration: NTR-1210. ER -