RT Journal Article SR Electronic T1 Single-joint Assessment for the Evaluation of Intraarticular Treatment: Responsiveness and Discrimination of the Composite Change Index JF The Journal of Rheumatology JO J Rheumatol FD The Journal of Rheumatology SP 1672 OP 1676 DO 10.3899/jrheum.140956 VO 42 IS 9 A1 Caroline J. Aalbers A1 Danielle M. Gerlag A1 Margriet J. Vervoordeldonk A1 Paul P. Tak A1 Robert B. Landewé YR 2015 UL http://www.jrheum.org/content/42/9/1672.abstract AB Objective. To investigate responsiveness, discrimination, and construct validity of a composite change index (CCI) for the assessment of single-joint involvement in inflammatory arthritis.Methods. Evaluation of standardized response means (SRM), Guyatt effect size, and Spearman rank correlation coefficient in a randomized controlled trial investigating the effect of an intraarticular etanercept injection.Results. The CCI showed a high SRM (1.68) and high Guyatt effect size (2.72). Both visual analog scale of pain and functionality had a moderate Guyatt effect size (2.06, 2.44) and high SRM (0.81, 0.97).Conclusion. This study supports the use of the CCI as a single-joint assessment after single-joint intervention. Clinical trial registration: NTR-1210.