%0 Journal Article %A Caroline J. Aalbers %A Danielle M. Gerlag %A Margriet J. Vervoordeldonk %A Paul P. Tak %A Robert B. Landewé %T Single-joint Assessment for the Evaluation of Intraarticular Treatment: Responsiveness and Discrimination of the Composite Change Index %D 2015 %R 10.3899/jrheum.140956 %J The Journal of Rheumatology %P 1672-1676 %V 42 %N 9 %X Objective. To investigate responsiveness, discrimination, and construct validity of a composite change index (CCI) for the assessment of single-joint involvement in inflammatory arthritis.Methods. Evaluation of standardized response means (SRM), Guyatt effect size, and Spearman rank correlation coefficient in a randomized controlled trial investigating the effect of an intraarticular etanercept injection.Results. The CCI showed a high SRM (1.68) and high Guyatt effect size (2.72). Both visual analog scale of pain and functionality had a moderate Guyatt effect size (2.06, 2.44) and high SRM (0.81, 0.97).Conclusion. This study supports the use of the CCI as a single-joint assessment after single-joint intervention. Clinical trial registration: NTR-1210. %U https://www.jrheum.org/content/jrheum/42/9/1672.full.pdf