RT Journal Article
SR Electronic
T1 Novel Ultrasound Joint Selection Methods Using a Reduced Joint Number Demonstrate Inflammatory Improvement when Compared to Existing Methods and Disease Activity Score at 28 Joints
JF The Journal of Rheumatology
JO J Rheumatol
FD The Journal of Rheumatology
SP 34
OP 37
DO 10.3899/jrheum.150590
VO 43
IS 1
A1 Tan, York Kiat
A1 Allen, John C.
A1 Lye, Weng Kit
A1 Conaghan, Philip G.
A1 D’Agostino, Maria Antonietta
A1 Chew, Li-Ching
A1 Thumboo, Julian
YR 2016
UL http://www.jrheum.org/content/43/1/34.abstract
AB Objective. A pilot study testing novel ultrasound (US) joint-selection methods in rheumatoid arthritis.Methods. Responsiveness of novel [individualized US (IUS) and individualized composite US (ICUS)] methods were compared with existing US methods and the Disease Activity Score at 28 joints (DAS28) for 12 patients followed for 3 months. IUS selected up to 7 and 12 most ultrasonographically inflamed joints, while ICUS additionally incorporated clinically symptomatic joints.Results. The existing, IUS, and ICUS methods’ standardized response means were −0.39, −1.08, and −1.11, respectively, for 7 joints; −0.49, −1.00, and −1.16, respectively, for 12 joints; and −0.94 for DAS28.Conclusion. Novel methods effectively demonstrate inflammatory improvement when compared with existing methods and DAS28.